Euphrosyne may refer to:
- 31 Euphrosyne, one of the largest main belt asteroids
- Boloria euphrosyne, a butterfly
- Euphrosyne (mythology), Greek goddess
People named Euphrosyne:
- Euphrosyne (9th century), Byzantine Empress
- Euphrosyne Angelina, daughter of Byzantine emperor Isaac II Angelus
- Euphrosyne Doukaina Kamatera (1155-1211), Byzantine empress
- Euphrosyne of Alexandria (5th century), legendary virgin
- Euphrosyne of Kiev, wife of king Géza II of Hungary
- Euphrosyne of Polatsk (1110-1173), Belarusian saint
- Euphrosyne Parepa-Rosa, 1872 recipient of the Gold Medal of the Royal Philharmonic Society
- Saint Euphrosyne of Moscow (died 1407), Grand Duchess of Muscovy
- Julia Nyberg, (1784-1854), Swedish poet (used the name as her pseudonym)
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